The three figures represented on this amulet are collectively known as the Osirian triad, due largely for their involvement in the Osiris creation myth. Isis and Nephthys were sisters, and the former was known as the wife of Osiris. Both goddesses were responsible for the care of Osiris’ body, having been killed by Set and protection of the infant Horus. Their outstretched hands, in intimate gesture of embrace, signifies their protective nature. Both goddesses were associated with rebirth and played a part in the funeral rites. Such amulets would have been worn to bestow the same level of care and protection offered to Horus, to the deceased. All three deities were part of the Heliopolis Ennead, which was formed of nine or ten principle Egyptian deities. These included the sun-god Atum; his children Shu and Tefnut; their children Geb and Nut; and their children Osiris, Isis, Set, and Nephthys. Horus was also often included.
To discover more about amulets in the Ancient Egyptian world, please visit our relevant post: Amulets in Ancient Egypt.